Metabolic Research
Semaglutide
GLP-1 receptor agonist approved in the United States for specific diabetes and weight-management indications, depending on product and labeling.
EstablishedApproved medicine
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This category covers peptides studied for effects on glucose control, appetite signaling, adipose tissue, and related metabolic processes. Approved medicines and experimental compounds are listed together, with evidence level shown on each profile.
Metabolic Research
GLP-1 receptor agonist approved in the United States for specific diabetes and weight-management indications, depending on product and labeling.
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Metabolic Research
Dual GIP and GLP-1 receptor agonist approved in the United States for specific diabetes and weight-related indications, depending on product labeling.
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Growth Hormone Research
Growth hormone–releasing factor analog approved to reduce excess abdominal fat in HIV-infected adults with lipodystrophy — not a general weight-loss medicine.
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Growth Hormone Research
Older ghrelin-receptor GH secretagogue known experimentally to stimulate GH and, in some contexts, appetite. Not an approved medicine.
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Metabolic Research
Mitochondrial-derived peptide studied in cell and mouse metabolic models. Human therapeutic use is not established.
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Metabolic Research
Modified fragment of human growth hormone studied historically for metabolic hypotheses. Not an established approved obesity medicine.
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